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LMU - Klinikum der Universität München - Medizinische Klinik und Poliklinik III

Marchioninistr. 15
D-81377 München
Leitung: Prof. Dr. med. Dr. rer. nat. Michael von Bergwelt

Studien

  • INTEGRATE ATMP
  • A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
  • CAR-T-cell Treatment for Untreated High Risk MANtle Cell Lymphoma (CARMAN)
  • An Adaptive Open-label Multicentre Phase 1/​2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/​Refractory Acute Myeloid Leukaemia (RESOLVE AML001)
  • Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies
  • A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (CARTITUDE-5)
  • A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL) (TRANSCEND FL)
  • Tisagenlecleucel in Adult Patients With Aggressive B-cell Non-Hodgkin Lymphoma (BELINDA)
  • Phase 1 Study of UniCAR02-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies
  • Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients (CASSIOPEIA)
  • MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM)
  • A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas (TRANSFORM)
  • Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
  • Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (ZUMA-4)

Kontakt

Univ.-Prof. Dr. med. Marion Subklewe
Leitung des CAR-T-Zell-Programms
marion.subklewe@med.uni-muenchen.de
+49 (0)89 4400-73133
Dr. med. Christian Schmidt
Stellv. Leiter Studienzentrale für Hämatologie
christian_schmidt@med.uni-muenchen.de
+49 (0)89 4400-77907
Dr. med. Veit Bücklein
veit.buecklein@med.lmu.de
+49 (0)89 4400-75551
Stefanie Grießhammer
Koordinatorin CAR-T-Zell-Therapie
cart@med.lmu.de
+49 (0)89 4400-73096

Studien

  • INTEGRATE ATMP
  • A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)
  • CAR-T-cell Treatment for Untreated High Risk MANtle Cell Lymphoma (CARMAN)
  • An Adaptive Open-label Multicentre Phase 1/​2 Trial, to Determine the Recommended Phase 2 Dose of CCTx-001, and to Assess Safety, Tolerability, and Clinical Activity in Patients With Relapsed/​Refractory Acute Myeloid Leukaemia (RESOLVE AML001)
  • Phase 1 Study of Allo-RevCAR01-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies
  • A Study of Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Cilta-cel, a CAR-T Therapy Directed Against BCMA Versus VRd Followed by Lenalidomide and Dexamethasone (Rd) Therapy in Participants With Newly Diagnosed Multiple Myeloma for Whom ASCT is Not Planned as Initial Therapy (CARTITUDE-5)
  • A Study to Evaluate the Efficacy and Safety of JCAR017 in Adult Subjects With Relapsed or Refractory Indolent B-cell Non-Hodgkin Lymphoma (NHL) (TRANSCEND FL)
  • Tisagenlecleucel in Adult Patients With Aggressive B-cell Non-Hodgkin Lymphoma (BELINDA)
  • Phase 1 Study of UniCAR02-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies
  • Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients (CASSIOPEIA)
  • MB-CART19.1 r/r CD19+ B-cell Malignancies (BCM)
  • A Study to Compare the Efficacy and Safety of JCAR017 to Standard of Care in Adult Subjects With High-risk, Transplant-eligible Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphomas (TRANSFORM)
  • Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
  • Study Evaluating Brexucabtagene Autoleucel (KTE-X19) in Pediatric and Adolescent Participants With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia or Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma (ZUMA-4)
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